Shuang Huang, PhD
Professor
Teaching Profile
Research Profile
Research in the Huang lab is concentrated on elucidating molecular mechanisms associated with breast and ovarian cancer metastasis. One of the current projects is to investigate how homeobox domain-containing proteins SHOX2 and HOXC8 regulate breast cancer metastasis with the focus on their role in epithelial-mesenchymal transition (EMT). Another project is based on our early discovery that the integrity of EPS8/ABI1/SOS1 tri-complex is critical for ovarian cancer metastasis. In this project, we are currently dissecting the players and pathways pertinent to the metastasis-promoting role of EPS8/ABI1/SOS1 tri-complex in ovarian cancer. In addition, the Huang lab is also working on identifying cancer driver genes/pathways in ovarian cancer, with the emphasis on developing targeted therapeutic strategies against ovary malignancies.
RESEARCH PROJECTS
Role of SHOX2 in breast tumor progression and metastasis R01, National Cancer Institute (CA187152) August 1, 2014 to July 31, 2019
Potential of Targeting PDE1C/2A for Suppressing Metastatic Ovarian Cancers Pilot Award, Department of Defense Ovarian Cancer Research Program July 1, 2013 to June 30, 2015
0000-0002-9674-2249
Publications
Grants
Education
Contact Details
- Business:
- (352) 273-6769
- Business:
- shuanghuang@ufl.edu
- Business Mailing:
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PO Box 103633
GAINESVILLE FL 32610 - Business Street:
-
CGRC 355
2033 MOWRY RD
Gainesville FL 32610